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Epigenetic Silencing of CHOP Expression by the Histone Methyltransferase EHMT1 Regulates Apoptosis in Colorectal Cancer Cells

Colorectal cancer (CRC) has a high mortality rate among cancers worldwide. To reduce this mortality rate, chemotherapy (5-fluorouracil, oxaliplatin, and irinotecan) or targeted therapy (bevacizumab, cetuximab, and panitumumab) has been used to treat CRC. However, due to various side effects and poor...

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Detalles Bibliográficos
Autores principales: Kim, Kwangho, Ryu, Tae Young, Lee, Jinkwon, Son, Mi-Young, Kim, Dae-Soo, Kim, Sang Kyum, Cho, Hyun-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448644/
https://www.ncbi.nlm.nih.gov/pubmed/35748228
http://dx.doi.org/10.14348/molcells.2022.0014