Cargando…
Epigenetic Silencing of CHOP Expression by the Histone Methyltransferase EHMT1 Regulates Apoptosis in Colorectal Cancer Cells
Colorectal cancer (CRC) has a high mortality rate among cancers worldwide. To reduce this mortality rate, chemotherapy (5-fluorouracil, oxaliplatin, and irinotecan) or targeted therapy (bevacizumab, cetuximab, and panitumumab) has been used to treat CRC. However, due to various side effects and poor...
Autores principales: | Kim, Kwangho, Ryu, Tae Young, Lee, Jinkwon, Son, Mi-Young, Kim, Dae-Soo, Kim, Sang Kyum, Cho, Hyun-Soo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448644/ https://www.ncbi.nlm.nih.gov/pubmed/35748228 http://dx.doi.org/10.14348/molcells.2022.0014 |
Ejemplares similares
-
EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression
por: Lee, Jinkwon, et al.
Publicado: (2021) -
Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis
por: Kim, Kwangho, et al.
Publicado: (2023) -
Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer
por: Ryu, Tae Young, et al.
Publicado: (2019) -
The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer
por: Kim, Seon-Kyu, et al.
Publicado: (2018) -
Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer
por: Ryu, Tae Young, et al.
Publicado: (2022)