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Lysosome Inhibition Reduces Basal and Nutrient-Induced Fat Accumulation in Caenorhabditis elegans
A long-term energy nutritional imbalance fundamentally causes the development of obesity and associated fat accumulation. Lysosomes, as nutrient-sensing and lipophagy centers, critically control cellular lipid catabolism in response to nutrient deprivation. However, whether lysosome activity is dire...
Autores principales: | Lu, Rui, Chen, Juan, Wang, Fangbin, Wang, Lu, Liu, Jian, Lin, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448645/ https://www.ncbi.nlm.nih.gov/pubmed/36058890 http://dx.doi.org/10.14348/molcells.2022.0073 |
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