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TREM2/β-catenin attenuates NLRP3 inflammasome-mediated macrophage pyroptosis to promote bacterial clearance of pyogenic bacteria

Triggering receptors expressed on myeloid cells 2 (TREM2) is considered a protective factor to protect host from bacterial infection, while how it elicits this role is unclear. In the present study, we demonstrate that deficiency of triggering receptors expressed on myeloid cells 2 (TREM2) significa...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Cao, Can, Zhu, Yanting, Fan, Huifeng, Liu, Qiaojuan, Liu, Yiting, Chen, Kang, Wu, Yongjian, Liang, Siping, Li, Meiyu, Li, Lexi, Liu, Xi, Zhang, Yuanqing, Wu, Chenglin, Lu, Gen, Wu, Minhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448748/
https://www.ncbi.nlm.nih.gov/pubmed/36068223
http://dx.doi.org/10.1038/s41419-022-05193-x