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MVsim is a toolset for quantifying and designing multivalent interactions

Arising through multiple binding elements, multivalency can specify the avidity, duration, cooperativity, and selectivity of biomolecular interactions, but quantitative prediction and design of these properties has remained challenging. Here we present MVsim, an application suite built around a conf...

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Detalles Bibliográficos
Autores principales: Bruncsics, Bence, Errington, Wesley J., Sarkar, Casim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448752/
https://www.ncbi.nlm.nih.gov/pubmed/36068204
http://dx.doi.org/10.1038/s41467-022-32496-6