Cargando…

S1PR1 induces metabolic reprogramming of ceramide in vascular endothelial cells, affecting hepatocellular carcinoma angiogenesis and progression

Angiogenesis is a fundamental process underlying the occurrence, growth and metastasis of hepatocellular carcinoma (HCC), a prevalent tumour type with an extremely poor prognosis due to abundant vasculature. However, the underlying mechanism of angiogenesis in HCC remains largely unknown. Herein, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xuehong, Qiu, Zhidong, Dong, Wei, Yang, Zebin, Wang, Junnan, Xu, Hailiang, Sun, Tian, Huang, Zhaoquan, Jin, Junfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448762/
https://www.ncbi.nlm.nih.gov/pubmed/36068200
http://dx.doi.org/10.1038/s41419-022-05210-z