Cargando…

S1PR1 induces metabolic reprogramming of ceramide in vascular endothelial cells, affecting hepatocellular carcinoma angiogenesis and progression

Angiogenesis is a fundamental process underlying the occurrence, growth and metastasis of hepatocellular carcinoma (HCC), a prevalent tumour type with an extremely poor prognosis due to abundant vasculature. However, the underlying mechanism of angiogenesis in HCC remains largely unknown. Herein, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xuehong, Qiu, Zhidong, Dong, Wei, Yang, Zebin, Wang, Junnan, Xu, Hailiang, Sun, Tian, Huang, Zhaoquan, Jin, Junfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448762/ https://www.ncbi.nlm.nih.gov/pubmed/36068200 http://dx.doi.org/10.1038/s41419-022-05210-z

Ejemplares similares

Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma
por: Dong, Wei, et al.
Publicado: (2022)

GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway
por: Qiu, Zhidong, et al.
Publicado: (2022)

Lipopolysaccharide and palmitic acid synergistically induced MCP-1 production via MAPK-meditated TLR4 signaling pathway in RAW264.7 cells
por: Wang, Xuehong, et al.
Publicado: (2019)

Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia
por: Dou, Yong-Qing, et al.
Publicado: (2020)

Potential biomarkers Ang II/AT1R and S1P/S1PR1 predict the prognosis of hepatocellular carcinoma
por: Ji, Yuanyuan, et al.
Publicado: (2020)

Ceramide and Regulation of Vascular Tone
por: Cogolludo, Angel, et al.
Publicado: (2019)

Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway
por: Zhou, Caixia, et al.
Publicado: (2022)

Reprogramming towards endothelial cells for vascular regeneration
por: Hong, Xuechong, et al.
Publicado: (2016)

Ceramide and ceramide 1-phosphate in health and disease
por: Arana, Lide, et al.
Publicado: (2010)

Rac1, caveolin-1 and vascular endothelial growth factor -mediated liver sinusoidal endothelial cell angiogenesis
por: Braet, Filip
Publicado: (2009)

BRG1 Activates PR65A Transcription to Regulate NO Bioavailability in Vascular Endothelial Cells
por: Chen, Baoyu, et al.
Publicado: (2020)

Overexpression of Twist1 in vascular endothelial cells promotes pathological retinal angiogenesis in mice
por: Zhang, Lin, et al.
Publicado: (2022)

S1PR1 and VEGFR2 – a synergy that promotes tumor angiogenesis?
por: Balaji Ragunathrao, Vijay Avin, et al.
Publicado: (2020)

Implication of Ceramide, Ceramide 1-Phosphate and Sphingosine 1-Phosphate in Tumorigenesis
por: Gangoiti, Patricia, et al.
Publicado: (2008)

Plumbagin restrains hepatocellular carcinoma angiogenesis by suppressing the migration and invasion of tumor-derived vascular endothelial cells
por: Wei, YanFei, et al.
Publicado: (2017)

Metabolic Reprogramming of Vascular Endothelial Cells: Basic Research and Clinical Applications
por: Peng, Hanlin, et al.
Publicado: (2021)

Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands
por: Staquicini, Daniela I., et al.
Publicado: (2023)

Endoplasmic reticulum resident oxidase ERO1-Lalpha promotes hepatocellular carcinoma metastasis and angiogenesis through the S1PR1/STAT3/VEGF-A pathway
por: Yang, Shikun, et al.
Publicado: (2018)

Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation
por: Syed, Shahzad Nawaz, et al.
Publicado: (2019)

Involvement of Heme Oxygenase-1 in Orexin-A-induced Angiogenesis in Vascular Endothelial Cells
por: Kim, Mi-Kyoung, et al.
Publicado: (2015)

Positive and Negative Regulation of Angiogenesis by Soluble Vascular Endothelial Growth Factor Receptor-1
por: Failla, Cristina M., et al.
Publicado: (2018)

YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA
por: Yang, Wendong, et al.
Publicado: (2019)

VASCULAR-1 and VASCULAR-2 as a New Potential Angiogenesis and Endothelial Dysfunction Markers in Peripheral Arterial Disease
por: Wieczór, Radosław, et al.
Publicado: (2019)

Update on the Role of the Endothelial Glycocalyx in Angiogenesis and Vascular Inflammation
por: Hu, Zhengping, et al.
Publicado: (2021)

Reprogramming Human Endothelial to Hematopoietic Cells Requires Vascular Induction
por: Sandler, Vladislav M., et al.
Publicado: (2014)

Caveolin-1 Knockdown Decreases SMMC7721 Human Hepatocellular Carcinoma Cell Invasiveness by Inhibiting Vascular Endothelial Growth Factor-Induced Angiogenesis
por: Zhang, Zhi-Bo, et al.
Publicado: (2020)

FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis
por: Zhu, Xiaolong, et al.
Publicado: (2022)

Anti-Vascular Endothelial Growth Factor Agents for Ocular Angiogenesis and Vascular Permeability
por: Kubota, Toshiaki, et al.
Publicado: (2012)

Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature
por: Kim, Harold, et al.
Publicado: (2010)

Corrigendum: YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA
por: Yang, Wendong, et al.
Publicado: (2022)

Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma
por: Wang, Zheng, et al.
Publicado: (2017)

Purinergic regulation of vascular endothelial growth factor signaling in angiogenesis
por: Rumjahn, S M, et al.
Publicado: (2009)

Mechanoregulation of Vascular Endothelial Growth Factor Receptor 2 in Angiogenesis
por: Miller, Bronte, et al.
Publicado: (2022)

Active Immunization Against the Vascular Endothelial Growth Factor Receptor flk1 Inhibits Tumor Angiogenesis and Metastasis
por: Li, Yiwen, et al.
Publicado: (2002)

Fisetin inhibits vascular endothelial growth factor-induced angiogenesis in retinoblastoma cells
por: Wang, Liangjun, et al.
Publicado: (2020)

Acetylbritannilactone Modulates Vascular Endothelial Growth Factor Signaling and Regulates Angiogenesis in Endothelial Cells
por: Zhao, Jingshan, et al.
Publicado: (2016)

Vascular Permeability Factor/Vascular Endothelial Growth Factor Induces Lymphangiogenesis as well as Angiogenesis
por: Nagy, Janice A., et al.
Publicado: (2002)

Proangiogenic Interactions of Vascular Endothelial MMP14 With VEGF Receptor 1 in VEGFA-Mediated Corneal Angiogenesis
por: Han, Kyu-Yeon, et al.
Publicado: (2016)

Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF
por: Cheng, Jiao, et al.
Publicado: (2019)

Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis
por: Corlan, Ana Silvia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_i9ug8qdivuo9a8lc14g9mqt44o