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Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis
Enzymes with high activity are readily produced through protein engineering, but intentionally and efficiently engineering enzymes for an expanded substrate scope is a contemporary challenge. One approach to address this challenge is Substrate Multiplexed Screening (SUMS), where enzyme activity is m...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448781/ https://www.ncbi.nlm.nih.gov/pubmed/36068220 http://dx.doi.org/10.1038/s41467-022-32789-w |