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Multiplexed mobilization and expression of biosynthetic gene clusters

Bacterial genomes contain large reservoirs of biosynthetic gene clusters (BGCs) that are predicted to encode unexplored natural products. Heterologous expression of previously unstudied BGCs should facilitate the discovery of additional therapeutically relevant bioactive molecules from bacterial cul...

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Detalles Bibliográficos
Autores principales: Libis, Vincent, MacIntyre, Logan W., Mehmood, Rabia, Guerrero, Liliana, Ternei, Melinda A., Antonovsky, Niv, Burian, Ján, Wang, Zongqiang, Brady, Sean F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448795/
https://www.ncbi.nlm.nih.gov/pubmed/36068239
http://dx.doi.org/10.1038/s41467-022-32858-0