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Multiplexed mobilization and expression of biosynthetic gene clusters
Bacterial genomes contain large reservoirs of biosynthetic gene clusters (BGCs) that are predicted to encode unexplored natural products. Heterologous expression of previously unstudied BGCs should facilitate the discovery of additional therapeutically relevant bioactive molecules from bacterial cul...
Autores principales: | Libis, Vincent, MacIntyre, Logan W., Mehmood, Rabia, Guerrero, Liliana, Ternei, Melinda A., Antonovsky, Niv, Burian, Ján, Wang, Zongqiang, Brady, Sean F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448795/ https://www.ncbi.nlm.nih.gov/pubmed/36068239 http://dx.doi.org/10.1038/s41467-022-32858-0 |
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