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Molecular pathogenesis of desmoid tumor and the role of γ-secretase inhibition

Desmoid tumor (DT) is a rare, soft tissue neoplasm associated with an unpredictable clinical course. Although lacking metastatic potential, DT is often locally aggressive and invasive, causing significant morbidity. Both sporadic DT and familial adenomatous polyposis (FAP)-associated DT are linked t...

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Detalles Bibliográficos
Autor principal: Federman, Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448813/
https://www.ncbi.nlm.nih.gov/pubmed/36068332
http://dx.doi.org/10.1038/s41698-022-00308-1