Cargando…
Effects of CYP2C19 and CYP2D6 gene variants on escitalopram and aripiprazole treatment outcome and serum levels: results from the CAN-BIND 1 study
Cytochrome P450 drug-metabolizing enzymes may contribute to interindividual differences in antidepressant outcomes. We investigated the effects of CYP2C19 and CYP2D6 gene variants on response, tolerability, and serum concentrations. Patients (N = 178) were treated with escitalopram (ESC) from weeks...
Autores principales: | Islam, Farhana, Marshe, Victoria S., Magarbeh, Leen, Frey, Benicio N., Milev, Roumen V., Soares, Claudio N., Parikh, Sagar V., Placenza, Franca, Strother, Stephen C., Hassel, Stefanie, Taylor, Valerie H., Leri, Francesco, Blier, Pierre, Uher, Rudolf, Farzan, Faranak, Lam, Raymond W., Turecki, Gustavo, Foster, Jane A., Rotzinger, Susan, Kennedy, Sidney H., Müller, Daniel J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448818/ https://www.ncbi.nlm.nih.gov/pubmed/36068210 http://dx.doi.org/10.1038/s41398-022-02124-4 |
Ejemplares similares
-
Pretreatment anxious depression as a predictor of side effect frequency and severity in escitalopram and aripiprazole adjunctive therapy
por: Espinola, Caroline W., et al.
Publicado: (2022) -
Prediction of depression treatment outcome from multimodal data: a CAN-BIND-1 report
por: Sajjadian, Mehri, et al.
Publicado: (2023) -
Developing an Electroencephalography-Based Model for Predicting Response to Antidepressant Medication
por: Schwartzmann, Benjamin, et al.
Publicado: (2023) -
Use of Machine Learning for Predicting Escitalopram Treatment Outcome From Electroencephalography Recordings in Adult Patients With Depression
por: Zhdanov, Andrey, et al.
Publicado: (2020) -
Predicting escitalopram treatment response from pre-treatment and early response resting state fMRI in a multi-site sample: A CAN-BIND-1 report
por: Harris, Jacqueline K., et al.
Publicado: (2022)