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Metformin suppresses proliferation and differentiation induced by BMP9 via AMPK signaling in human fetal lung fibroblast-1

Adenosine monophosphosphate-activated protein kinase (AMPK) and its activator metformin were found to be involved in the regulation of fibroblast activation and pulmonary fibrosis. However, the regulatory mechanism has been undetermined. Recently, AMPK has been reported to exert its effect through i...

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Detalles Bibliográficos
Autores principales: Chen, Qiongfeng, Wang, Yaqun, Sheng, Linna, Huang, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448853/
https://www.ncbi.nlm.nih.gov/pubmed/36091775
http://dx.doi.org/10.3389/fphar.2022.984730