Cargando…
Metformin suppresses proliferation and differentiation induced by BMP9 via AMPK signaling in human fetal lung fibroblast-1
Adenosine monophosphosphate-activated protein kinase (AMPK) and its activator metformin were found to be involved in the regulation of fibroblast activation and pulmonary fibrosis. However, the regulatory mechanism has been undetermined. Recently, AMPK has been reported to exert its effect through i...
Autores principales: | Chen, Qiongfeng, Wang, Yaqun, Sheng, Linna, Huang, Yonghong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448853/ https://www.ncbi.nlm.nih.gov/pubmed/36091775 http://dx.doi.org/10.3389/fphar.2022.984730 |
Ejemplares similares
-
Exogenous BMP9 promotes lung fibroblast HFL-1 cell activation via ALK1/Smad1/5 signaling in vitro
por: Wang, Yaqun, et al.
Publicado: (2021) -
MYH9 Inhibition Suppresses TGF-β1-Stimulated Lung Fibroblast-to-Myofibroblast Differentiation
por: Sun, Xionghua, et al.
Publicado: (2021) -
Metformin attenuates fibroblast activation during pulmonary fibrosis by targeting S100A4 via AMPK-STAT3 axis
por: Ji, Huimin, et al.
Publicado: (2023) -
Metformin Modulates High Glucose-Incubated Human Umbilical Vein Endothelial Cells Proliferation and Apoptosis Through AMPK/CREB/BDNF Pathway
por: Han, Xiqiong, et al.
Publicado: (2018) -
Activating AMPK to Restore Tight Junction Assembly in Intestinal Epithelium and to Attenuate Experimental Colitis by Metformin
por: Chen, Lu, et al.
Publicado: (2018)