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Toll-like receptor signaling pathway triggered by inhibition of serpin A1 stimulates production of inflammatory cytokines by endometrial stromal cells

Endometriosis is characterized by the presence of inflamed and fibrotic endometrial tissue outside the uterine cavity. Previously, we found decreased SERPINA1 (alpha-1 antitrypsin) expression in endometriosis-like lesions in a mouse model of endometriosis, suggesting that it exacerbated inflammation...

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Detalles Bibliográficos
Autores principales: Kusama, Kazuya, Satoyoshi, Ayaka, Azumi, Mana, Yoshie, Mikihiro, Kojima, Junya, Mizuno, Yumi, Ono, Masanori, Nishi, Hirotaka, Kajihara, Takeshi, Tamura, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448891/
https://www.ncbi.nlm.nih.gov/pubmed/36093086
http://dx.doi.org/10.3389/fendo.2022.966455