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Toll-like receptor signaling pathway triggered by inhibition of serpin A1 stimulates production of inflammatory cytokines by endometrial stromal cells
Endometriosis is characterized by the presence of inflamed and fibrotic endometrial tissue outside the uterine cavity. Previously, we found decreased SERPINA1 (alpha-1 antitrypsin) expression in endometriosis-like lesions in a mouse model of endometriosis, suggesting that it exacerbated inflammation...
Autores principales: | Kusama, Kazuya, Satoyoshi, Ayaka, Azumi, Mana, Yoshie, Mikihiro, Kojima, Junya, Mizuno, Yumi, Ono, Masanori, Nishi, Hirotaka, Kajihara, Takeshi, Tamura, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448891/ https://www.ncbi.nlm.nih.gov/pubmed/36093086 http://dx.doi.org/10.3389/fendo.2022.966455 |
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