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Recent findings in the regulation of G6PD and its role in diseases

Glucose-6-phosphate dehydrogenase (G6PD) is the only rate-limiting enzyme in the pentose phosphate pathway (PPP). Rapidly proliferating cells require metabolites from PPP to synthesize ribonucleotides and maintain intracellular redox homeostasis. G6PD expression can be abnormally elevated in a varie...

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Detalles Bibliográficos
Autores principales: Meng, Qingfei, Zhang, Yanghe, Hao, Shiming, Sun, Huihui, Liu, Bin, Zhou, Honglan, Wang, Yishu, Xu, Zhi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448902/
https://www.ncbi.nlm.nih.gov/pubmed/36091812
http://dx.doi.org/10.3389/fphar.2022.932154