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Hunting for the cause: Evidence for prion-like mechanisms in Huntington’s disease

The hypothesis that pathogenic protein aggregates associated with neurodegenerative diseases spread from cell-to-cell in the brain in a manner akin to infectious prions has gained substantial momentum due to an explosion of research in the past 10–15 years. Here, we review current evidence supportin...

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Detalles Bibliográficos
Autores principales: Donnelly, Kirby M., Coleman, Cevannah M., Fuller, Madison L., Reed, Victoria L., Smerina, Dayna, Tomlinson, David S., Pearce, Margaret M. Panning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448931/
https://www.ncbi.nlm.nih.gov/pubmed/36090278
http://dx.doi.org/10.3389/fnins.2022.946822