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Hunting for the cause: Evidence for prion-like mechanisms in Huntington’s disease
The hypothesis that pathogenic protein aggregates associated with neurodegenerative diseases spread from cell-to-cell in the brain in a manner akin to infectious prions has gained substantial momentum due to an explosion of research in the past 10–15 years. Here, we review current evidence supportin...
Autores principales: | Donnelly, Kirby M., Coleman, Cevannah M., Fuller, Madison L., Reed, Victoria L., Smerina, Dayna, Tomlinson, David S., Pearce, Margaret M. Panning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448931/ https://www.ncbi.nlm.nih.gov/pubmed/36090278 http://dx.doi.org/10.3389/fnins.2022.946822 |
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