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Dimethyl fumarate eliminates differentially culturable Mycobacterium tuberculosis in an intranasal murine model of tuberculosis

Tuberculosis (TB) claims nearly 1.5 million lives annually. Current TB treatment requires a combination of several drugs administered for at least 6 months. Mycobacterium tuberculosis (Mtb), the causative agent of TB, can persist in infected humans and animals for decades. Moreover, during infection...

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Detalles Bibliográficos
Autores principales: Glenn, Sarah M., Turapov, Obolbek, Makarov, Vadim, Kell, Douglas B., Mukamolova, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449328/
https://www.ncbi.nlm.nih.gov/pubmed/36093181
http://dx.doi.org/10.3389/fcimb.2022.957287