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Creatinine accelerates APAP-induced liver damage by increasing oxidative stress through ROS/JNK signaling pathway

Serum creatinine is an endogenous biomarker to estimate glomerular filtration rate (GFR) and is commonly used to assess renal function in clinical practice. Acetaminophen (APAP), the most available analgesic and antipyretic medication, is recommended as the drug of choice for pain control in patient...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Liu, Yan, Peng, Qifeng, Wang, Guodong, Tan, Qing, Ou, Zhongyue, Xu, Qishan, Liu, Chixiang, Zuo, Daming, Zhao, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449354/
https://www.ncbi.nlm.nih.gov/pubmed/36091804
http://dx.doi.org/10.3389/fphar.2022.959497