Cargando…
Creatinine accelerates APAP-induced liver damage by increasing oxidative stress through ROS/JNK signaling pathway
Serum creatinine is an endogenous biomarker to estimate glomerular filtration rate (GFR) and is commonly used to assess renal function in clinical practice. Acetaminophen (APAP), the most available analgesic and antipyretic medication, is recommended as the drug of choice for pain control in patient...
Autores principales: | Liu, Fang, Liu, Yan, Peng, Qifeng, Wang, Guodong, Tan, Qing, Ou, Zhongyue, Xu, Qishan, Liu, Chixiang, Zuo, Daming, Zhao, Jianbo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449354/ https://www.ncbi.nlm.nih.gov/pubmed/36091804 http://dx.doi.org/10.3389/fphar.2022.959497 |
Ejemplares similares
-
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins
por: Su, Wen, et al.
Publicado: (2021) -
Modulation of HMGB1 Release in APAP-Induced Liver Injury: A Possible Strategy of Chikusetsusaponin V Targeting NETs Formation
por: Liu, Jian, et al.
Publicado: (2021) -
4-Hydroxyphenylacetic Acid Prevents Acute APAP-Induced Liver Injury by Increasing Phase II and Antioxidant Enzymes in Mice
por: Zhao, Hongqiong, et al.
Publicado: (2018) -
ROS/JNK/C-Jun Pathway is Involved in Chaetocin Induced Colorectal Cancer Cells Apoptosis and Macrophage Phagocytosis Enhancement
por: Wang, Huihui, et al.
Publicado: (2021) -
Isoorientin Ameliorates APAP-Induced Hepatotoxicity via Activation Nrf2 Antioxidative Pathway: The Involvement of AMPK/Akt/GSK3β
por: Fan, Xiaoye, et al.
Publicado: (2018)