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A novel form of docetaxel polymeric micelles demonstrates anti-tumor and ascites-inhibitory activities in animal models as monotherapy or in combination with anti-angiogenic agents

Malignant ascites (MA) is caused by intraperitoneal spread of solid tumor cells and results in a poor quality of life. Chemotherapy is a common first-line treatment for patients with MA. Taxotere (®) (DTX) is widely used in solid tumor therapies. However, the low water solubility and side effects ca...

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Detalles Bibliográficos
Autores principales: Guo, Leilei, Qin, Xiaokang, Xue, Liting, Yang, Janine Y., Zhang, Yumei, Zhu, Shunwei, Ye, Gang, Tang, Renhong, Yang, WenQing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449419/
https://www.ncbi.nlm.nih.gov/pubmed/36091776
http://dx.doi.org/10.3389/fphar.2022.964076