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Fluorescently labeled nuclear morphology is highly informative of neurotoxicity

Neurotoxicity can be detected in live microscopy by morphological changes such as retraction of neurites, fragmentation, blebbing of the neuronal soma and ultimately the disappearance of fluorescently labeled neurons. However, quantification of these features is often difficult, low-throughput, and...

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Detalles Bibliográficos
Autores principales: Wang, Shijie, Linsley, Jeremy W., Linsley, Drew A., Lamstein, Josh, Finkbeiner, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449453/
https://www.ncbi.nlm.nih.gov/pubmed/36093369
http://dx.doi.org/10.3389/ftox.2022.935438