BMS‐202, a PD‐1/PD‐L1 inhibitor, decelerates the pro‑fibrotic effects of fibroblasts derived from scar tissues via ERK and TGFβ1/Smad signaling pathways

INTRODUCTION: Hypertrophic scar (HS), a fibroproliferative disorder of the skin with some tumor‐like properties, is closely related to dysregulated inflammation. PD‐1/PD‐L1 inhibitor is a promising medication for cancer therapy as its potent functions on adaptive immune response; whether it could be...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Yuanyuan, Xiao, Min, Li, Xinqing, Zhou, Shanyu, Sun, Yangyang, Yu, Wenyuan, Zhao, Tianlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449589/
https://www.ncbi.nlm.nih.gov/pubmed/36169254
http://dx.doi.org/10.1002/iid3.693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449589/
https://www.ncbi.nlm.nih.gov/pubmed/36169254
http://dx.doi.org/10.1002/iid3.693

Ejemplares similares