A type IV Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis

The lysophosphatidic acid (LPA) signaling axis is an important but rather underexplored pathway in liver disease. LPA is predominantly produced by Autotaxin (ATX) that has gained significant attention with an impressive number of ATX inhibitors (type I‐IV) reported. Here, we evaluated the therapeuti...

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Detalles Bibliográficos
Autores principales: Booijink, Richell, Salgado‐Polo, Fernando, Jamieson, Craig, Perrakis, Anastassis, Bansal, Ruchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449594/
https://www.ncbi.nlm.nih.gov/pubmed/35833384
http://dx.doi.org/10.15252/emmm.202216333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449594/
https://www.ncbi.nlm.nih.gov/pubmed/35833384
http://dx.doi.org/10.15252/emmm.202216333

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