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A type IV Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis
The lysophosphatidic acid (LPA) signaling axis is an important but rather underexplored pathway in liver disease. LPA is predominantly produced by Autotaxin (ATX) that has gained significant attention with an impressive number of ATX inhibitors (type I‐IV) reported. Here, we evaluated the therapeuti...
Autores principales: | Booijink, Richell, Salgado‐Polo, Fernando, Jamieson, Craig, Perrakis, Anastassis, Bansal, Ruchi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449594/ https://www.ncbi.nlm.nih.gov/pubmed/35833384 http://dx.doi.org/10.15252/emmm.202216333 |
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