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Multimerization of Ebola GPΔmucin on protein nanoparticle vaccines has minimal effect on elicitation of neutralizing antibodies

Ebola virus (EBOV), a member of the Filoviridae family of viruses and a causative agent of Ebola Virus Disease (EVD), is a highly pathogenic virus that has caused over twenty outbreaks in Central and West Africa since its formal discovery in 1976. The only FDA-licensed vaccine against Ebola virus, r...

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Detalles Bibliográficos
Autores principales: Powell, Abigail E., Xu, Duo, Roth, Gillie A., Zhang, Kaiming, Chiu, Wah, Appel, Eric A., Kim, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449635/
https://www.ncbi.nlm.nih.gov/pubmed/36091016
http://dx.doi.org/10.3389/fimmu.2022.942897