Transplantation of IGF-1-induced BMSC-derived NPCs promotes tissue repair and motor recovery in a rat spinal cord injury model

Bone marrow-derived mesenchymal stem cells (BMSCs) have therapeutic potential for spinal cord injury (SCI). We have shown that insulin-like growth factor 1 (IGF-1) enhances the cellular proliferation and survivability of BMSCs-derived neural progenitor cells (NPCs) by downregulating miR-22-3p. Howev...

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Detalles Bibliográficos
Autores principales: Al-Zikri, Putri Nur Hidayah, Huat, Tee Jong, Khan, Amir Ali, Patar, Azim, Reza, Mohammed Faruque, Idris, Fauziah Mohamad, Abdullah, Jafri Malin, Jaafar, Hasnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449758/
https://www.ncbi.nlm.nih.gov/pubmed/36090221
http://dx.doi.org/10.1016/j.heliyon.2022.e10384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449758/
https://www.ncbi.nlm.nih.gov/pubmed/36090221
http://dx.doi.org/10.1016/j.heliyon.2022.e10384

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