Cargando…

Characterization of Membrane-Type Dissolution Profiles of Clinically Available Orally Inhaled Products Using a Weibull Fit and a Mechanistic Model

[Image: see text] Dissolution rate impacts the absorption rate of poorly soluble inhaled drugs. In vitro dissolution tests that can capture the impact of changes in critical quality attributes of the drug product on in vivo dissolution are important for the development of products containing poorly...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Zwaan, Irès, Franek, Frans, Fransson, Rebecca, Tehler, Ulrika, Frenning, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449970/
https://www.ncbi.nlm.nih.gov/pubmed/35939615
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00177