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Hispanic ethnicity and the rs4880 variant in SOD2 are associated with elevated liver enzymes and bilirubin levels in children receiving asparaginase-containing chemotherapy for acute lymphoblastic leukemia

Asparaginase is an integral component of acute lymphoblastic leukemia (ALL)() treatment. Hepatotoxicity related to asparaginase is one of the most common treatment-related toxicities in ALL therapy. Hispanic children are at higher risk of developing ALL, and toxicities from ALL therapy. The rs4880 v...

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Detalles Bibliográficos
Autores principales: Wu, Sharon, Wang, Mengxi, Alqahtani, Amani, Lou, Mimi, Stock, Wendy, Bhojwani, Deepa, Alachkar, Houda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450009/
https://www.ncbi.nlm.nih.gov/pubmed/35658244
http://dx.doi.org/10.1016/j.biopha.2022.113000