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The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria
The emergence of Plasmodium falciparum (Pf) parasite strains tolerant of the artemisinin component and resistant to the other drug component in artemisinin combination therapies (ACTs) used for treatment now markedly complicates malaria control. Thus, development of new combination therapies are urg...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450014/ https://www.ncbi.nlm.nih.gov/pubmed/36091789 http://dx.doi.org/10.3389/fphar.2022.957690 |