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The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria

The emergence of Plasmodium falciparum (Pf) parasite strains tolerant of the artemisinin component and resistant to the other drug component in artemisinin combination therapies (ACTs) used for treatment now markedly complicates malaria control. Thus, development of new combination therapies are urg...

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Detalles Bibliográficos
Autores principales:	Watson, Daniel J., Laing, Lizahn, Beteck, Richard M., Gibhard, Liezl, Haynes, Richard K., Wiesner, Lubbe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450014/ https://www.ncbi.nlm.nih.gov/pubmed/36091789 http://dx.doi.org/10.3389/fphar.2022.957690

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