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Passive immunization with equine RBD-specific Fab protects K18-hACE2-mice against Alpha or Beta variants of SARS-CoV-2

Emergence of variants of concern (VOC) during the COVID-19 pandemic has contributed to the decreased efficacy of therapeutic monoclonal antibody treatments for severe cases of SARS-CoV-2 infection. In addition, the cost of creating these therapeutic treatments is high, making their implementation in...

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Detalles Bibliográficos
Autores principales: Barbier, Mariette, Lee, Katherine S., Vikharankar, Mayur S., Rajpathak, Shriram N., Kadam, Nandkumar, Wong, Ting Y., Russ, Brynnan P., Cyphert, Holly A., Miller, Olivia A., Rader, Nathaniel A., Cooper, Melissa, Kang, Jason, Sen-Kilic, Emel, Wong, Zeriel Y., Winters, Michael T., Bevere, Justin R., Martinez, Ivan, Devarumath, Rachayya, Shaligram, Umesh S., Damron, F. Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450042/
https://www.ncbi.nlm.nih.gov/pubmed/36091051
http://dx.doi.org/10.3389/fimmu.2022.948431