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Changes in chromatin accessibility are not concordant with transcriptional changes for single‐factor perturbations

A major goal in the field of transcriptional regulation is the mapping of changes in the binding of transcription factors to the resultant changes in gene expression. Recently, methods for measuring chromatin accessibility have enabled us to measure changes in accessibility across the genome, which...

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Detalles Bibliográficos
Autores principales: Kiani, Karun, Sanford, Eric M, Goyal, Yogesh, Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450098/
https://www.ncbi.nlm.nih.gov/pubmed/36069349
http://dx.doi.org/10.15252/msb.202210979