RGD peptide-based lipids for targeted mRNA delivery and gene editing applications

mRNA therapeutics are promising platforms for protein replacement therapies and gene editing technologies. When delivered via non-viral gene delivery systems, such as lipid nanoparticles (LNPs), mRNA therapeutics are easy to produce and show low toxicity and immunogenicity. However, LNPs show limite...

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Detalles Bibliográficos
Autores principales: Qin, Jingya, Xue, Lulu, Gong, Ningqiang, Zhang, Hanwen, Shepherd, Sarah J., Haley, Rebecca M., Swingle, Kelsey L., Mitchell, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450108/
https://www.ncbi.nlm.nih.gov/pubmed/36199352
http://dx.doi.org/10.1039/d2ra02771b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450108/
https://www.ncbi.nlm.nih.gov/pubmed/36199352
http://dx.doi.org/10.1039/d2ra02771b

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