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RGD peptide-based lipids for targeted mRNA delivery and gene editing applications
mRNA therapeutics are promising platforms for protein replacement therapies and gene editing technologies. When delivered via non-viral gene delivery systems, such as lipid nanoparticles (LNPs), mRNA therapeutics are easy to produce and show low toxicity and immunogenicity. However, LNPs show limite...
Autores principales: | Qin, Jingya, Xue, Lulu, Gong, Ningqiang, Zhang, Hanwen, Shepherd, Sarah J., Haley, Rebecca M., Swingle, Kelsey L., Mitchell, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450108/ https://www.ncbi.nlm.nih.gov/pubmed/36199352 http://dx.doi.org/10.1039/d2ra02771b |
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