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Normics: Proteomic Normalization by Variance and Data-Inherent Correlation Structure

Several algorithms for the normalization of proteomic data are currently available, each based on a priori assumptions. Among these is the extent to which differential expression (DE) can be present in the dataset. This factor is usually unknown in explorative biomarker screens. Simultaneously, the...

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Detalles Bibliográficos
Autores principales: Dressler, Franz F., Brägelmann, Johannes, Reischl, Markus, Perner, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450154/
https://www.ncbi.nlm.nih.gov/pubmed/35853575
http://dx.doi.org/10.1016/j.mcpro.2022.100269