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Discrepancy between distribution of alpha-synuclein oligomers and Lewy-related pathology in Parkinson’s disease

The pathological hallmarks of Parkinson’s disease (PD) are α-synuclein (αSYN)-positive inclusions referred to as Lewy bodies and Lewy neurites, collectively referred to as Lewy-related pathology (LRP). LRP is thought to propagate in an ascending manner throughout the brain as the disease progresses....

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Detalles Bibliográficos
Autores principales: Sekiya, Hiroaki, Tsuji, Asato, Hashimoto, Yuki, Takata, Mariko, Koga, Shunsuke, Nishida, Katsuya, Futamura, Naonobu, Kawamoto, Michi, Kohara, Nobuo, Dickson, Dennis W., Kowa, Hisatomo, Toda, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450240/
https://www.ncbi.nlm.nih.gov/pubmed/36068646
http://dx.doi.org/10.1186/s40478-022-01440-6