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Discrepancy between distribution of alpha-synuclein oligomers and Lewy-related pathology in Parkinson’s disease
The pathological hallmarks of Parkinson’s disease (PD) are α-synuclein (αSYN)-positive inclusions referred to as Lewy bodies and Lewy neurites, collectively referred to as Lewy-related pathology (LRP). LRP is thought to propagate in an ascending manner throughout the brain as the disease progresses....
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450240/ https://www.ncbi.nlm.nih.gov/pubmed/36068646 http://dx.doi.org/10.1186/s40478-022-01440-6 |