TMBur: a distributable tumor mutation burden approach for whole genome sequencing

BACKGROUND: Tumor mutation burden (TMB) is a key characteristic used in a tumor-type agnostic context to inform the use of immune checkpoint inhibitors (ICI). Accurate and consistent measurement of TMB is crucial as it can significantly impact patient selection for therapy and clinical trials, with...

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Detalles Bibliográficos
Autores principales: Titmuss, Emma, Corbett, Richard D., Davidson, Scott, Abbasi, Sanna, Williamson, Laura M., Pleasance, Erin D., Shlien, Adam, Renouf, Daniel J., Jones, Steven J. M., Laskin, Janessa, Marra, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450342/
https://www.ncbi.nlm.nih.gov/pubmed/36071521
http://dx.doi.org/10.1186/s12920-022-01348-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450342/
https://www.ncbi.nlm.nih.gov/pubmed/36071521
http://dx.doi.org/10.1186/s12920-022-01348-z

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