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Glucose transport engineering allows mimicking fed-batch performance in batch mode and selection of superior producer strains

BACKGROUND: Fed-batch mode is the standard culture technology for industrial bioprocesses. Nevertheless, most of the early-stage cell and process development is carried out in batch cultures, which can bias the initial selection of expression systems. Cell engineering can provide an alternative to f...

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Detalles Bibliográficos
Autores principales: Velazquez, Daniela, Sigala, Juan-Carlos, Martínez, Luz María, Gaytán, Paul, Gosset, Guillermo, Lara, Alvaro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450411/
https://www.ncbi.nlm.nih.gov/pubmed/36071458
http://dx.doi.org/10.1186/s12934-022-01906-1