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Glucose transport engineering allows mimicking fed-batch performance in batch mode and selection of superior producer strains
BACKGROUND: Fed-batch mode is the standard culture technology for industrial bioprocesses. Nevertheless, most of the early-stage cell and process development is carried out in batch cultures, which can bias the initial selection of expression systems. Cell engineering can provide an alternative to f...
Autores principales: | Velazquez, Daniela, Sigala, Juan-Carlos, Martínez, Luz María, Gaytán, Paul, Gosset, Guillermo, Lara, Alvaro R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450411/ https://www.ncbi.nlm.nih.gov/pubmed/36071458 http://dx.doi.org/10.1186/s12934-022-01906-1 |
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