Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo

BACKGROUND: Immunotherapy based on Bi-specific T Cell Engagers (TCE) represents one of the most attractive strategy to treat cancers resistant to conventional therapies. TCE are antibody-like proteins that simultaneously bind with one arm to a Tumor Associated Antigen (TAA) on cancer cells and with...

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Detalles Bibliográficos
Autores principales: Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Inoue, Toshikazu, Nakamura, Koji, De Lorenzo, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450414/
https://www.ncbi.nlm.nih.gov/pubmed/36071464
http://dx.doi.org/10.1186/s13046-022-02474-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450414/
https://www.ncbi.nlm.nih.gov/pubmed/36071464
http://dx.doi.org/10.1186/s13046-022-02474-3

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