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Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model

BACKGROUND: Mesenchymal stem cell (MSCs)-derived small Extracellular Vesicles (sEVs) are considered as a new cell-free therapy for pain caused by nerve injury, but whether human placental mesenchymal stem cell-derived sEVs relieve pain in sciatic nerve injury and its possible mechanism are still unc...

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Detalles Bibliográficos
Autores principales: Lu, Yitian, Zhang, Jintao, Zeng, Fanning, Wang, Peng, Guo, Xiangna, Wang, Haitao, Qin, Zaisheng, Tao, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450435/
https://www.ncbi.nlm.nih.gov/pubmed/36071475
http://dx.doi.org/10.1186/s12974-022-02578-9