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Inadvertent Transfer of Murine VL30 Retrotransposons to CAR-T Cells

For more than a decade, genetically engineered autologous T-cells have been successfully employed as immunotherapy drugs for patients with incurable blood cancers. The active components in some of these game-changing medicines are autologous T-cells that express viral vector-delivered chimeric antig...

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Detalles Bibliográficos
Autores principales: Lee, Sung Hyun, Hao, Yajing, Gui, Tong, Dotti, Gianpietro, Savoldo, Barbara, Zou, Fei, Kafri, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450689/
https://www.ncbi.nlm.nih.gov/pubmed/36081760
http://dx.doi.org/10.1155/2022/6435077