Liproxstatin-1 induces cell cycle arrest, apoptosis, and caspase-3/GSDME-dependent secondary pyroptosis in K562 cells

Leukemia is a fatal hematopoietic disorder with a poor prognosis. Drug resistance is inevitable after the long-term use of chemotherapeutic agents. Liproxstatin-1, commonly known as a ferroptosis inhibitor, has never been reported to have anticancer effects. In the present study, the antileukemic ro...

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Detalles Bibliográficos
Autores principales: Dong, Hai-Qun, Liang, Shi-Jing, Xu, Yu-Ling, Dai, Yi, Sun, Na, Deng, Dong-Hong, Cheng, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450809/
https://www.ncbi.nlm.nih.gov/pubmed/36004469
http://dx.doi.org/10.3892/ijo.2022.5409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450809/
https://www.ncbi.nlm.nih.gov/pubmed/36004469
http://dx.doi.org/10.3892/ijo.2022.5409

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