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A phosphoinositide signalling pathway mediates rapid lysosomal repair
Lysosomal dysfunction has been increasingly linked to disease and normal ageing(1,2). Lysosomal membrane permeabilization (LMP), a hallmark of lysosome-related diseases, can be triggered by diverse cellular stressors(3). Given the damaging contents of lysosomes, LMP must be rapidly resolved, althoug...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450835/ https://www.ncbi.nlm.nih.gov/pubmed/36071159 http://dx.doi.org/10.1038/s41586-022-05164-4 |