Glucocorticoids enhance chemotherapy-driven stress granule assembly and impair granule dynamics, leading to cell death

Stress granules (SGs) can assemble in cancer cells upon chemotoxic stress. Glucocorticoids function during stress responses and are administered with chemotherapies. The roles of glucocorticoids in SG assembly and disassembly pathways are unknown. We examined whether combining glucocorticoids such a...

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Detalles Bibliográficos
Autores principales: Schwed-Gross, Avital, Hamiel, Hila, Faber, Gabriel P., Angel, Mor, Ben-Yishay, Rakefet, Benichou, Jennifer I. C., Ishay-Ronen, Dana, Shav-Tal, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450892/
https://www.ncbi.nlm.nih.gov/pubmed/35713120
http://dx.doi.org/10.1242/jcs.259629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450892/
https://www.ncbi.nlm.nih.gov/pubmed/35713120
http://dx.doi.org/10.1242/jcs.259629

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