AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability

PINK1 accumulation at the outer mitochondrial membrane (OMM) is a key event required to signal depolarized mitochondria to the autophagy machinery. How this early step is, in turn, modulated by autophagy proteins remains less characterized. Here, we show that, upon mitochondrial depolarization, the...

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Detalles Bibliográficos
Autores principales: Di Rienzo, Martina, Romagnoli, Alessandra, Ciccosanti, Fabiola, Refolo, Giulia, Consalvi, Veronica, Arena, Giuseppe, Valente, Enza Maria, Piacentini, Mauro, Fimia, Gian Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450973/
https://www.ncbi.nlm.nih.gov/pubmed/34798798
http://dx.doi.org/10.1080/15548627.2021.1997052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450973/
https://www.ncbi.nlm.nih.gov/pubmed/34798798
http://dx.doi.org/10.1080/15548627.2021.1997052

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